DOXORUBICIN-RESISTANCE MEDIATED BY HYPOXIA CONTROLS APOPTOSIS IN COLON CANCER CELLS
- At: 2015 FIP Congress in Düsseldorf (Germany)
- Type: Poster
- By: PINZON-DAZA, Martha (UNIVERSIDAD DEL ROSARIO, UNIT OF BIOCHEMISTRY, BOGOTA, Colombia)
- Co-author(s): Yenith Cuellar, Marcela Rojas, Alejandro Ondo, Fabio Castillo, Lilia Del Riesgo, Ruth Garzón, UNIVERSIDAD DEL ROSARIO GROUP BIO-BIO, FACULTY OF NATURAL SCIENCES AND MATHEMATICS Bogota, Colombia
Activation of chemotherapy resistance mechanisms could be related to MDR (Multidrug resistance) phenotype and its induction could depend on oxidative stress cellular response originated from hypoxia or drug use. The correlation of hypoxia-inducible factor-1 alpha (HIF-1α), the amount of Reactive Oxygen Species (ROS) and its effect on multidrug.. The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.