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DOXORUBICIN-RESISTANCE MEDIATED BY HYPOXIA CONTROLS APOPTOSIS IN COLON CANCER CELLS

  • At: 2015 FIP Congress in Düsseldorf (Germany)
  • Type: Poster
  • By: PINZON-DAZA, Martha (UNIVERSIDAD DEL ROSARIO, UNIT OF BIOCHEMISTRY, BOGOTA, Colombia)
  • Co-author(s): Yenith Cuellar, Marcela Rojas, Alejandro Ondo, Fabio Castillo, Lilia Del Riesgo, Ruth Garzón, UNIVERSIDAD DEL ROSARIO GROUP BIO-BIO, FACULTY OF NATURAL SCIENCES AND MATHEMATICS Bogota, Colombia
  • Abstract:

    Activation of chemotherapy resistance mechanisms could be related to MDR (Multidrug resistance) phenotype and its induction could depend on oxidative stress cellular response originated from hypoxia or drug use. The correlation of hypoxia-inducible factor-1 alpha (HIF-1α), the amount of Reactive Oxygen Species (ROS) and its effect on multidrug

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Last update 4 October 2019

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