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VARIABILITY IN ORAL BIOAVAILABILITY AND LYMPHATIC TRANSPORT OF POORLY WATER SOLUBLE, LIPOPHILIC DRUGS

  • At: 2015 FIP Congress in Düsseldorf (Germany)
  • Type: Presentation
  • By: TREVASKIS, Natalie (Monash Institute of Pharmaceutical Sciences, Drug Delivery, Disposition and Dynamics, Parkville, Australia)
  • Co-author(s): Natalie L Trevaskis
  • Abstract:

    Approximately 40% of currently marketed drugs and most current drug development candidates can be classified as poorly water soluble (PWS). PWS drugs are predisposed to low and variable oral absorption and therefore clinical response. This is because drug molecules must, in most cases, be in solution to be absorbed and the solubilisation of PWS

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Last update 4 October 2019

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