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DELINEATING INTER-INDIVIDUAL VARIABILITY IN SYSTEMIC EXPOSURE OF ORAL GABAPENTIN

  • At: 2015 FIP Congress in Düsseldorf (Germany)
  • Type: Presentation
  • By: PAULETTI, Giovanni (University of Cincinnati, Winkle College of Pharmacy, Cincinnati, United States)
  • Co-author(s): Giovanni Pauletti
  • Abstract:

    Clinical trials demonstrated that oral gabapentin is effective in managing pain symptoms associated with postherpetic neuralgia. Unfortunately, the pharmacodynamic response is inconsistent, with less than half of the patients experiencing > 50% improvement in pain scores when compared to baseline. To explore underlying mechanisms of this

    ..

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Last update 4 October 2019

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