DELINEATING INTER-INDIVIDUAL VARIABILITY IN SYSTEMIC EXPOSURE OF ORAL GABAPENTIN
- At: 2015 FIP Congress in Düsseldorf (Germany)
- Type: Presentation
- By: PAULETTI, Giovanni (University of Cincinnati, Winkle College of Pharmacy, Cincinnati, United States)
- Co-author(s): Giovanni Pauletti
Clinical trials demonstrated that oral gabapentin is effective in managing pain symptoms associated with postherpetic neuralgia. Unfortunately, the pharmacodynamic response is inconsistent, with less than half of the patients experiencing > 50% improvement in pain scores when compared to baseline. To explore underlying mechanisms of this.. The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.