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DIVERSITY OF DRUG HYPERSENSITIVITY GENES WITH SPECIAL REFERENCE TO COLD MEDICINE-RELATED STEVENS-JOHNSON SYNDROME

  • At: 2015 FIP Congress in Düsseldorf (Germany)
  • Type: Presentation
  • By: TOKUNAGA, Katsushi (Graduate School of Medicine, University of Tokyo, Department of Human Genetics, Tokyo, Japan)
  • Co-author(s): Katsushi TOKUNAGA
  • Abstract:

    We investigate a specific type of SJS/TEN, accompanied by eye manifestations and related to certain types of cold remedies.  Association with HLA-A*02:06 was found in Japanese and replicated in Korean.  In silico docking simulations predicted that the A0206 molecule has high binding affinities to various ingredients including ethenzamide and

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Last update 4 October 2019

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