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THE GENETIC, CELLULAR AND MOLECULAR BASIS OF IDIOSYNCRATIC DRUG TOXICITY

  • At: 2015 FIP Congress in Düsseldorf (Germany)
  • Type: Presentation
  • By: PARK, Kevin (University of Liverpool, Institute of Translational Medicine, Liverpool, United Kingdom)
  • Co-author(s): Kevin Park
  • Abstract:

    Adverse drug reactions (ADRs) remain a major problem in the clinic and in drug development, of particular concern are those ADRs of an idiosyncratic nature. Such reactions are still poorly understood, but nevertheless often assumed to be immunological in nature. Recent advances in pharmacogenetics, most notably HLA restriction, have provided the

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Last update 4 October 2019

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