Radix sophorae flavescentis-radix liquiritiae herb pair resists concanacalin a induced liver injury through inhibition of endoplasmic reticulum stress

• In: Posters: Pharmacokinetics/Pharmacodynamics & Systems Pharmacology
• At: Bangkok (Thailand) (2014)
• Type: Poster
• Poster code: POS-PAA007
• By: DANG, Xueliang (Fourth Military Medical University, Department of Pharmacy, Tangdu Hospital, Xi'an, China)
• Co-author(s): Zhang, Yan (Fourth Military Medical University, Xi'an, China)
  Shi, Lei (Fourth Military Medical University, Xi'an, China)
  Hu, Na (Fourth Military Medical University, Xi'an, China)
  Guo, Shun (Fourth Military Medical University, Xi'an, China)
  Zhao, Jun (Fourth Military Medical University, Xi'an, China)
  Tian, Ye (Fourth Military Medical University, Xi'an, China)
  
• Abstract:

  The combination of Radix Sophorae flavescentis and Radix Liquiritiae has a significant therapeutic effect for liver injury, but the mechanism remains unclear. Endoplasmic reticulum (ER) stress plays a great role in liver disease, which is also an important pathway to concanacalin A (Con A) induced liver injury. We speculated that Radix Sophorae..

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