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Stereoselective determination of eslicarbazepine acetate (bia 2-093) and its metabolites in plasma by HPLC-UV

  • At: 2006 FIP Congress in Salvadore (Brazil)
  • Type: Poster
  • By: CARAMONA, Maria Margarida (Coimbra University, Coimbra, Portugal)
  • Co-author(s): Alves (Coimbra University, COIMBRA, Portugal)
    Falcao (Coimbra University, COIMBRA, Portugal)
    Figueiredo (Coimbra University, COIMBRA, Portugal)
    Castel-Branco (Coimbra University, COIMBRA, Portugal)
  • Abstract:

    Aim: To validate a simple and economical HPLC-UV method for simultaneous and stereoselective determination of eslicarbazepine acetate (BIA 2-093) and its metabolites BIA 2-194, BIA 2-195 and oxcarbazepine (OXC) in plasma. BIA 2-093 is a new antiepileptic drug structurally related to carbamazepine and OXC, which is under development at Laboratórios

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Last update 4 October 2019

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