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Raloxifene loaded solid lipid nanoparticles for enhanced oral bioavailability

  • At: 2014 FIP Congress in Bangkok (Thailand)
  • Type: Poster
  • By: YONG, Chul Soon (Yeungnam University, College of Pharmacy, Gyeongsangbuk-do, South-Korea)
  • Co-author(s): Tran, Tuan Hiep (Yeungnam University, Gyeongsangbuk-do, South-Korea)
    Kim, Jong Oh (Yeungnam University, Gyeongsangbuk-do, South-Korea)
    Jeong, Jee-Heon (Yeungnam University, Gyeongsangbuk-do, South-Korea)
    Choi, Han-Gon (2College of Pharmacy, Hanyang University, Ansan, South-Korea)
    Tak, Jin Wook (Yeungnam University, Gyeongsangbuk-do, South-Korea)
    Choi, Ju Yeon (Yeungnam University, Gyeongsangbuk-do, South-Korea)
    Truong Duy, Hieu (Yeungnam University, Gyeongsangbuk-do, South-Korea)
  • Abstract:

    Background and Aims: Solid lipid nanoparticles (SLNs) of poor orally bioavailable drug raloxifene were prepared using hot emulsification technique.

    Methods: The SLN were characterized for size, zeta potential, entrapment efficiency (EE), drug release, physical properties and pharmacokinetics study. The optimized SLN formulation exhibited a..

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Last update 4 October 2019

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