Formulation and development of chitosan based in situ thermosensitive injectable hydrogel of pegylated melphalan conjugates
- At: 2014 FIP Congress in Bangkok (Thailand)
- Type: Poster
- By: SARAF, Shailendra (University Institute of Pharmacy, Pharmacy, Raipur, chhattisgarh, India)
- Co-author(s): Saraf, Swarnlata (University Institute of Pharmacy, Raipur, chhattisgarh, India)
Alexander, Amit (University Institute of Pharmacy, Raipur, chhattisgarh, India)
To reduce the burst effect and to provide a controlled release, a blend of Chitosan(CS)/glycerophosphate disodium (GP) thermosensitive hydrogels were prepared for the sustained delivery of an alkylating agent, melphalan (ML).
In the present study, poorly soluble alkylating drug, melphalan (ML) is PEGylated with linear methoxy poly .. The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.