Preparation and characterization of binary amorphous precipitates of ritonavir and quercetin
- At: 2014 FIP Congress in Bangkok (Thailand)
- Type: Poster
- By: DENGALE, Swapnil (Manipal college of pharmaceutical sciences, Department of Pharmaceutical Quality Assurance, Manipal, India)
- Co-author(s): Ranjan, Om Prakash (Manipal college of pharmaceutical sciences, Manipal, India)
Bhat, Krishnamurthy (Manipal college of pharmaceutical sciences, Manipal, India)
I Background: Ritonavir is the protease inhibitor with very low bioavailability due to its limited aqueous solubility (BCS Class-II member). Several attempts have been made to stabilize amorphous form of Ritonavir. We attempted to stabilize Ritonavir in amorphous form by using binary amorphous technique with proven pg-p substrate and inhibitor.. The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.