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Preparation and characterization of binary amorphous precipitates of ritonavir and quercetin

  • At: 2014 FIP Congress in Bangkok (Thailand)
  • Type: Poster
  • By: DENGALE, Swapnil (Manipal college of pharmaceutical sciences, Department of Pharmaceutical Quality Assurance, Manipal, India)
  • Co-author(s): Ranjan, Om Prakash (Manipal college of pharmaceutical sciences, Manipal, India)
    Bhat, Krishnamurthy (Manipal college of pharmaceutical sciences, Manipal, India)
  • Abstract:

    I Background: Ritonavir is the protease inhibitor with very low bioavailability due to its limited aqueous solubility (BCS Class-II member). Several attempts have been made to stabilize amorphous form of Ritonavir. We attempted to stabilize Ritonavir in amorphous form by using binary amorphous technique with proven pg-p substrate and inhibitor..

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Last update 4 October 2019

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