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Formulation and development of in situ thermosensitive injectable hydrogel of pegylated melphalan conjugates from poloxamer (p407)

  • At: 2014 FIP Congress in Bangkok (Thailand)
  • Type: Poster
  • By: ALEXANDER, Amit (University Institute of Pharmacy,, Pharmacy, Raipur, India)
  • Co-author(s): Saraf, Swarnlata (University Institute of Pharmacy, Pt. Ravishankar Shukla University, Raipur, chhattisgarh, India)
    Saraf, Shailendra (University Institute of Pharmacy, Pt. Ravishankar Shukla University, Raipur, chhattisgarh, India)
  • Abstract:

    Background: Poloxamer 407 (P407), remain to be the most preferred biomaterial among the scientists for the formulation of in situ forming thermoresponsive hydrogels. In the present study, poorly soluble alkylating agent, melphalan (ML) also, known as L-Phenylalanine Mustard is PEGylated with linear methoxy poly (ethylene glycol) (MPEG) to form the ..

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Last update 4 October 2019

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