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Molecular docking and in silico adme study of novel n9-substituted purines targeting ck1 and abl-tyrosine kinase

  • At: 2014 FIP Congress in Bangkok (Thailand)
  • Type: Poster
  • By: FAWZY, Iten (Future University, Pharmaceutical Chemistry, Cairo, Egypt)
  • Co-author(s): Youssef, Khairia (Future University, Cairo, Egypt)
    Ismail, Nasser (Ain Shams University, Cairo, Egypt)
    Lasheen, Deena (Ain Shams University, Cairo, Egypt)
    Abouzid, Khaled (Ain Shams University, Cairo, Egypt)
    Mandour, Asmaa (, Cairo, Egypt)
  • Abstract:

    Background: Recent publications had presented compounds combining the purine system from the original cosubstrate ATP and phenyl moieties in order to explore possible interactions with the different regions of the ATP binding site in several disease-related protein kinases especially cancer. Aims: Novel N9-substitiuted purines were designed with..

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Last update 4 October 2019

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