Rage, receptor of advanced glycation endoproducts, negatively regulates chondrocytes differentiation.
- At: 2014 FIP Congress in Bangkok (Thailand)
- Type: Poster
- By: FUJITA, Takashi (Ritsumeikan Univ., Pharmaceutical Sciences, Kusatsu, Japan)
RAGE, receptor for advanced glycation endoproducts (AGE), has been characterized as an activator of osteoclastgenesis, while it was not clear whether RAGE directly regulate chondrocytes proliferation and differentiation or not. Here, we showed that RAGE has an inhibitory role for chondrocytes differentiation. RAGE expression was observed in.. The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.