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Two validated hplc methods for the simultaneous determination of ciprofloxacin hydrochloride and metronidazole in binary mixture and in the presence of ciprofloxacin acid degradation product- application to tablets

  • At: 2014 FIP Congress in Bangkok (Thailand)
  • Type: Poster
  • By: MANDOUR, Asmaa (Cairo, Egypt)
  • Co-author(s): El-Bagary, Ramzia (Cairo University, Giza, Egypt)
    El-Zaher, Asmaa (Cairo University, Giza, Egypt)
    Elkady, Ehab (Cairo University, Giza, Egypt)
    El-Hakeem, Maha (Cairo University, Giza, Egypt)
  • Abstract:

    Two HPLC methods are presented for the simultaneous determination of ciprofloxacin HCl (CIP) and metronidazole (MET) in binary mixture (Method 1) and in presence of ciprofloxacin acid degradation product (DEG) (Method 2). The methods were based on the chromatographic separation of the two drugs using Kromasil 100-5C18 (150 mm x 4.6 mm) with UV..

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Last update 4 October 2019

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