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Simultaneous determination of ciprofloxacin hydrochloride and metronidazole in spiked human plasma by ultra performance liquid chromatography-tandem mass spectroscopy

  • At: 2014 FIP Congress in Bangkok (Thailand)
  • Type: Poster
  • By: MANDOUR, Asmaa (Cairo, Egypt)
  • Co-author(s): El-Bagary, Ramzia (Cairo University, Giza, Egypt)
    El-Zaher, Asmaa (Cairo University, Giza, Egypt)
    Elkady, Ehab (Cairo University, Giza, Egypt)
  • Abstract:

    Ciprofloxacin HCl (CIP) and Metronidazole (MET) are antibacterial drugs used in combination for treatment of mixed aerobic/anaerobic infections. An UPLC-MS/MS method was developed for the simultaneous estimation of CIP and MET in spiked human plasma using sildenafil citrate as an internal standard (IS). Protein precipitation was used for analyte..

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Last update 4 October 2019

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