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Simultaneous and comprehensive in vivo analysis of cytochrome p450 activity by using a cocktail approach in rats

  • At: 2014 FIP Congress in PSWC, Melbourne (Australia)
  • Type: Presentation
  • By: UCHIDA, Shinya (University of Shizuoka, School of Pharmaceutical Sciences, Department of Pharmacy Practice & Science, Shizuoka, Japan)
  • Co-author(s): Tanaka, Shimako (University of Shizuoka, School of Pharmaceutical Sciences, Shizuoka, Japan)
    Namiki, Noriyuki (University of Shizuoka, School of Pharmaceutical Sciences, Shizuoka, Japan)
  • Abstract:

    Background: A cocktail approach can detect the activities of multiple cytochrome P450 (CYP) isoforms following the administration of multiple CYP-specific substrates in a single experiment. Few studies have reported the results of a comprehensive analysis of CYP activity in rats.
    Aims: The aim of this study was to develop a simultaneous and..

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Last update 4 October 2019

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