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Allosteric drug discovery at g protein-coupled receptors

  • At: 2014 FIP Congress in PSWC, Melbourne (Australia)
  • Type: Presentation
  • By: CHRISTOPOULOS, Arthur (Monash University, Drug Discovery Biology, Parkville, Australia)
  • Abstract:

    G protein-coupled receptors (GPCRs) are the largest family of receptors in the body. Less than 10% of the human GPCR complement already accounds for approximately 30% of all medicines on the market, highlighting their (patho)physiological relevance and tractability. Traditionally, optimizing the interaction of lead molecules with the binding site

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Last update 4 October 2019

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