Allosteric drug discovery at g protein-coupled receptors
- At: 2014 FIP Congress in PSWC, Melbourne (Australia)
- Type: Presentation
- By: CHRISTOPOULOS, Arthur (Monash University, Drug Discovery Biology, Parkville, Australia)
G protein-coupled receptors (GPCRs) are the largest family of receptors in the body. Less than 10% of the human GPCR complement already accounds for approximately 30% of all medicines on the market, highlighting their (patho)physiological relevance and tractability. Traditionally, optimizing the interaction of lead molecules with the binding site.. The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.