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An alternative high-performance liquid-chromatographic method for determination of diclofenac in pharmacokinetic studies.

  • At: 2006 FIP Congress in Salvadore (Brazil)
  • Type: Poster
  • By: MANFIO, Josélia (Biocinese - Centro de Estudos Biofar., Toledo, Brazil)
  • Co-author(s): MANFIO, Josélia (Biocinese - Centro de Estudos Biofar., TOLEDO, Brazil)
    Pugens, Ana Maria (Biocinese - Centro de Estudos Biofar., TOLEDO, Brazil)
    Dal' Maso, Alexandre (Biocinese - Centro de Estudos Biofar., TOLEDO, Brazil)
    Weich, Anelise (Prati, Donaduzzi & Cia Ltda, TOLEDO, Brazil)
  • Abstract:

    Diclofenac, 2-[(2,6-dichlorophenyl)amino]phenylacetic acid is non-steroidal anti-inflammatory (NSAIDs), analgesic, antipyretic drug. To measure diclofenac in plasma, several methods have been developed including high-performance liquid chromatography with UV detection. In the present study, an alternative, fully validated HPLC procedure employing..

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Last update 4 October 2019

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