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Buccal mucosal delivery of a peptide for the treatment of autoimmune diseases

  • At: 2014 FIP Congress in PSWC, Melbourne (Australia)
  • Type: Presentation
  • By: JIN, Liang (Monash University, Pharmaceutics, Melbourne, Australia)
  • Co-author(s): White, Paul (Monash University, Melbourne, Australia)
    Boyd, Ben (Monash University, Melbourne, Australia)
    Pennington, Mike (Peptides International, Louisville, United States of America)
    Norton, Raymond (Monash University, Melbourne, Australia)
    Nicolazzo, Joseph (Monash University, Melbourne, Australia)
  • Abstract:

    Background information: As a potent blocker of the voltage-gated potassium channel Kv1.3, ShK peptide can be potentially used as an immunomodulator for the treatment of autoimmune diseases. Indeed, ShK is currently undergoing Phase I clinical trials. However, systemic delivery of ShK is challenging as oral administration leads to poor..

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Last update 4 October 2019

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