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Sugar-based amphiphiles for drug delivery: synthesis, characterisation and prospects

  • At: 2014 FIP Congress in PSWC, Melbourne (Australia)
  • Type: Presentation
  • By: FEAST, George Charles (CSIRO, Materials Science & Engineering, Clayton south mdc, Australia)
  • Co-author(s): Lepitre (CSIRO, Clayton south mdc, Australia)
    Hutt (CSIRO, Clayton south mdc, Australia)
    Mulet (CSIRO, Clayton south mdc, Australia)
    Conn (CSIRO, Clayton south mdc, Australia)
    Drummond (CSIRO, Clayton south mdc, Australia)
    Savage (CSIRO, Clayton south mdc, Australia)
  • Abstract:

    Carbohydrate based drugs are underrepresented in the field of therapeutics despite the discovery of numerous carbohydrate binding proteins. Major obstacles for drug-development in this area include the high polarity of sugars, which restricts their ability to cross the enterocyte layer, and fast renal excretion when delivered orally. It is..

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Last update 4 October 2019

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