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Biomimetic glyceride prodrugs facilitate targeted delivery to the lymphatics, lymph nodes and adipose tissue

  • At: 2014 FIP Congress in PSWC, Melbourne (Australia)
  • Type: Presentation
  • By: TREVASKIS, Natalie (Monash Institute of Pharmaceutical Sciences, Drug Delivery, Disposition and Dynamics, Parkville, Australia)
  • Co-author(s): Loosli, Michaela (Monash Institute of Pharmaceutical Sciences, Parkville, Australia)
    Gracia, . (Monash Institute of Pharmaceutical Sciences, Parkville, Australia)
    Quach, Tim (Monash Institute of Pharmaceutical Sciences, Parkville, Australia)
    Simpson, Jamie (Monash Institute of Pharmaceutical Sciences, Parkville, Australia)
    Porter, Chris (Monash Institute of Pharmaceutical Sciences, Parkville, Australia)
  • Abstract:

    Background: The lymphatics play essential roles in immunity, cancer metastasis and dietary triglyceride transport, and interact with surrounding adipose. Strategies to deliver therapeutics (such as aspirin (ASP) which is anti-inflammatory and influences lymph vessel contractility) and imaging agents to lymphatics and adipose could thus improve..

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Last update 4 October 2019

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