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Idiosyncratic drug induced liver injury: from population to molecular target

  • At: 2014 FIP Congress in PSWC, Melbourne (Australia)
  • Type: Presentation
  • By: HO, Samuel (The University of Sydney, Faculty of Pharmacy, University of sydney, Australia)
  • Co-author(s): Hibbs, David (The University of Sydney, University of sydney, Australia)
    Chen, Timothy (The University of Sydney, University of sydney, Australia)
    Mclaclan, Andrew (The University of Sydney, University of sydney, Australia)
    Fois, Romano (The University of Sydney, University of sydney, Australia)
  • Abstract:

    Background: Idiosyncratic drug induced liver injury (iDILI) can lead to liver transplantation or death and is the leading reason for failure of drugs in development and attrition of marketed drugs. Currently no reliable methods exist to screen for toxic drugs or to identify at-risk individuals.
    Aims: This study aimed to develop and apply a method..

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Last update 4 October 2019

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