Electrostatically stabilized iron oxide nanoparticles for thermoresponsive cancer treatment

• In: SUBMITTED ORALS on Tuesday, 15 April 2014, 14:00-15:30
• At: PSWC, Melbourne (Australia) (2014)
• Type: Presentation
• By: PAULETTI, Giovanni M. (University of Cincinnati, James L. Winkle College of Pharmacy, Cincinnati, United States of America)
• Co-author(s): Allam, Ayat (University of Cincinnati, Cincinnati, United States of America)
  Potter, Sarah (University of Cincinnati, Cincinnati, United States of America)
  Mohamed, Dina (Faculty of Pharmacy, Assiut University, Assiut, Egypt)
  Habib, Fawzia (Faculty of Pharmacy, Assiut University, Assiut, Egypt)
  
• Abstract:

  Background: To limit undesired adverse events of chemotherapy, thermoresponsive nanocomposites loaded with potent anticancer agents allow selective, stimulus-induced drug release in close proximity to desired target cells mediated by magnetic hyperthermia.
  Methods: Superparamagentic Fe₃O₄ nanoparticles (SPIONs) were coated with a DPPC/DPPG (50:50) ..

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