Electrostatically stabilized iron oxide nanoparticles for thermoresponsive cancer treatment
- At: 2014 FIP Congress in PSWC, Melbourne (Australia)
- Type: Presentation
- By: PAULETTI, Giovanni M. (University of Cincinnati, James L. Winkle College of Pharmacy, Cincinnati, United States of America)
- Co-author(s): Allam, Ayat (University of Cincinnati, Cincinnati, United States of America)
Potter, Sarah (University of Cincinnati, Cincinnati, United States of America)
Mohamed, Dina (Faculty of Pharmacy, Assiut University, Assiut, Egypt)
Habib, Fawzia (Faculty of Pharmacy, Assiut University, Assiut, Egypt)
Background: To limit undesired adverse events of chemotherapy, thermoresponsive nanocomposites loaded with potent anticancer agents allow selective, stimulus-induced drug release in close proximity to desired target cells mediated by magnetic hyperthermia.
Methods: Superparamagentic Fe3O4 nanoparticles (SPIONs) were coated with a DPPC/DPPG (50:50) .. The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.