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Drug delivery to the brain by colloidal carrier systems

  • In: SUBMITTED ORALS on Tuesday, 15 April 2014, 14:00-15:30
  • At: PSWC, Melbourne (Australia) (2014)
  • Type: Presentation
  • By: FRICKER, Gert (Ruprecht-Karls-University Heidelberg, Institute of Pharmacy and Molecular Biotechnology, Heidelberg, Germany)
  • Co-author(s): Helm, Frieder (Ruprecht-Karls-University Heidelberg, Heidelberg, Germany)
    Reimold, Isolde (Ruprecht-Karls-University Heidelberg, Heidelberg, Germany)
    Tremmel, Robin (Ruprecht-Karls-University Heidelberg, Heidelberg, Germany)
    H, Uta (Ruprecht-Karls-University Heidelberg, Heidelberg, Germany)
  • Abstract:

    Background: Most drug candidates do not reach the CNS because they cannot cross the blood brain barrier (BBB) which is formed by brain capillary endothelial cells being connected by extremely tight junctions and being equipped with potent export-proteins recognizing a multitude of diverse substrates. Strategies to deliver drugs to the brain..

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Last update 4 October 2019

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