The value of not over-engineering - simple biocompatible nanoconstructs overcome mgst-1 mediated resistance in breast cancer
- At: 2014 FIP Congress in PSWC, Melbourne (Australia)
- Type: Presentation
- By: NYSTRöM, Andreas (Karolinska Instututet, Institute of Enviromental Medicine, Stockholm, Sweden)
- Co-author(s): Zeng, Xianghui (Karolinska Instututet, Stockholm, Sweden)
Resistance to single or multiple chemotherapeutic drugs is a major complication in clinical oncology and is one of the most common treatment limitations in patients with reoccurring cancers. Nanoparticle (NP)-based drug delivery systems (DDS's) have been shown to overcome drug resistance in cancer cells mainly by avoiding the activation of efflux.. The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.