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Predicting dosage form-dependent food effects with biorelevant multi-compartmental dissolution tests: case example nifedipine

  • At: 2014 FIP Congress in PSWC, Melbourne (Australia)
  • Type: Poster
  • By: ANDREAS, Cord Juergen (Institute of Pharmaceutical Technology, Frankfurt a. m., Germany)
  • Co-author(s): Muenster, Uwe (Bayer Pharma AG, Wuppertal, Germany)
    Dressman, Jennifer (Institute of Pharmaceutical Technology, Frankfurt a. m., Germany)
  • Abstract:

    Background
    Multi-compartmental dissolution apparatus like the USP apparatus III (BioDis) or IV (flow-through cell) offer the opportunity to easily exchange the dissolution media at various intervals throughout an experiment. With appropriate experimental conditions and dissolution media, the gastrointestinal tract in either the fasted or fed state ..

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Last update 4 October 2019

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