Predicting dosage form-dependent food effects with biorelevant multi-compartmental dissolution tests: case example nifedipine
- At: 2014 FIP Congress in PSWC, Melbourne (Australia)
- Type: Poster
- By: ANDREAS, Cord Juergen (Institute of Pharmaceutical Technology, Frankfurt a. m., Germany)
- Co-author(s): Muenster, Uwe (Bayer Pharma AG, Wuppertal, Germany)
Dressman, Jennifer (Institute of Pharmaceutical Technology, Frankfurt a. m., Germany)
Multi-compartmental dissolution apparatus like the USP apparatus III (BioDis) or IV (flow-through cell) offer the opportunity to easily exchange the dissolution media at various intervals throughout an experiment. With appropriate experimental conditions and dissolution media, the gastrointestinal tract in either the fasted or fed state .. The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.