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Yhp-743, a noval parp1/2 inhibitor for treatment of human triple-negative breast cancer with brca deficiency

  • At: PSWC, Melbourne (Australia) (2014)
  • Type: Poster
  • By: JI, Ming (Beijing, China)
  • Abstract:

    Triple-negative breast cancers (TNBC) occur more frequently in women, and the only available treatment for TNBC is chemotherapy. Targeting the nuclear enzyme Poly (ADP-ribose) Polymerase (PARP) represents a novel approach to treatment of TNBC. YHP-743, a potent small molecule inhibitor of PARP1/2, is being developed for treatment of..

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Last update 4 October 2019

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