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Targeted delivery of mycophenolic acid to the lymphatic system using lipid mimetic prodrugs: triglyceride vs phospholipid analogues

  • In: Posters C - Drug Design and Discovery
  • At: PSWC, Melbourne (Australia) (2014)
  • Type: Poster
  • Poster code: PC-030
  • By: HU, Luojuan (Monash University, Pharmaceutical Sciences, Melbourne, Australia)
  • Co-author(s): Quach, Tim (Monash University, Melbourne, Australia)
    Han, Sifei (Monash University, Melbourne, Australia)
    Trevaskis, Natalie (Monash University, Melbourne, Australia)
    Simpson, Jamie (Monash University, Melbourne, Australia)
    Porter, Christopher (Monash University, Melbourne, Australia)
  • Abstract:

    Background
    Enhanced delivery of immunomodulators to the lymphatics provides opportunities to selectively improve the treatment of immune disease, since the active sites of many immunomodulators are located in the lymphatics. Lipidic prodrugs where drug is covalently conjugated to a lipid moiety provide one approach to the promotion of lymphatic..

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Last update 28 September 2023

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