Expression and function of P-glycoprotein in alveolar epithelial cells and its modulation by cigarette smoke extract

• In: Posters
• At: Dublin (Ireland) (2013)
• Type: Poster
• By: YUMOTO, Ryoko (Hiroshima University, Graduate School of Biomedical & Health Sciences, Pharmaceutics and Therapeutics, Hiroshima, Japan)
• Co-author(s): Sasaki, Yoshihiro (Hiroshima University, Graduate School of Biomedical & Health Sciences, Hiroshima, Japan)
  Horiuchi, Taishi (Hiroshima University, Graduate School of Biomedical & Health Sciences, Hiroshima, Japan)
  Kato, Yuki (Hiroshima University, Graduate School of Biomedical & Health Sciences, Hiroshima, Japan)
  Kishimoto, Umi (Hiroshima University, Graduate School of Biomedical & Health Sciences, Hiroshima, Japan)
  Nagai, Junya (Hiroshima University, Graduate School of Biomedical & Health Sciences, Hiroshima, Japan)
  Takano, Mikihisa (Hiroshima University, Graduate School of Biomedical & Health Sciences, Hiroshima, Japan)
  
• Abstract:

  
  Background
  
  
  In the lung, various transporters are known to be expressed. However, the expression and function of P-glycoprotein (P-gp) in alveolar epithelial cells is still unclear. In addition, the lung is the organ directly exposed to cigarette smoke in smokers. However, the information concerning the effect of cigarette smoke on P-gp in
  ..

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