• Join
  • Login
  • Contact

Search abstracts

Design, synthesis, and biological evaluation of memantine-polyamine conjugates as NMDA channel blockers

  • At: Dublin (Ireland) (2013)
  • Type: Poster
  • By: KUMAMOOT, Takuya (Musashino University, Faculty of Pharmacy, Nishitokyo, Japan)
  • Co-author(s): Nakajima, M. (Musashino University, Nishitokyo, Japan)
    Katakawa, K. (Musashino University, Nishitokyo, Japan)
    Yoshizawa, Y. (Chiba University, Chiba, Japan)
    Saiki, R. (Chiba University, Chiba, Japan)
    Nishimura, K. (Chiba University, Chiba, Japan)
    Igarashi, K. (AminePharma, Chiba University, Chiba, Japan)
  • Abstract:

    1. Background

    N-Methyl-D-aspartate (NMDA) receptors have been implicated in learning and memory, and may also play a central role in various conditions leading to neuronal degradation. Overexcitation of NMDA receptors may result in neuronal cell injury or death. Therefore, NMDA receptor antagonists could be of therapeutic benefit to a number of..

  • The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress. Please login
Last update 4 October 2019

FIP Congresses