RP-HPLC method for determination of ofloxacin and its degradation products in tablets

• In: Laboratories and Medicines Control Services Section - Poster Session
• At: Salvadore (Brazil) (2006)
• Type: Poster
• Poster code: LMCS-P-001
• By: ZIVANOVIC, Ljiljana (Faculty of Pharmacy, Belgrade, Yugoslavia)
• Co-author(s): Zigic, Gordana (Medicines and Medical Devices Agency, BELGRADE, Serbia and Montenegro)
  Zecevic, Mira (Faculty of Pharmacy, Belgrade, BELGRADE, Serbia and Montenegro)
  
• Abstract:

  A quantitative RP-HPLC method was developed and validated for determination and assay of ofloxacin(OF) and its degradation products decarboxy ofloxacin (DOF), 9-piperazino ofloxacin (POF), des-methyl ofloxacin (MOF) and ofloxacin-N-oxide (NOF) in tablets. A RP-HPLC method was performed on XTERRA C18 column with hybrid particle technology at 45oC

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