Blood distribution of bortezomib and its kinetics in multiple myeloma patients

• In: SIG Posters
• At: Amsterdam (the Netherlands) (2012)
• Type: Poster
• Poster code: PAA-P-09
• By: OSAWA, Takashi (Hamamatsu University School of Medicine, Hospital Pharmacy, Hamamatsu, Japan)
• Co-author(s): Naito, T. (Hamamatsu University School of Medicine, Hamamatsu, Japan)
  Kaneko, T. (University of Shizuoka, Shizuoka, Japan)
  Mino, Y. (Hamamatsu University School of Medicine, Hamamatsu, Japan)
  Yamada, H. (University of Shizuoka, Shizuoka, Japan)
  Ohnishi, K. (Hamamatsu University School of Medicine, Hamamatsu, Japan)
  Kawakami, J. (Hamamatsu University School of Medicine, Hamamatsu, Japan)
  
• Abstract:

  Background:
  Bortezomib is a proteasome inhibitor that can be effective in the treatment of refractory and relapsed multiple myeloma. Pharmacokinetic disposition of bortezomib has not been fully characterized in humans.
  Aims:
  The aim of this study was to evaluate the blood distribution of bortezomib and its kinetics in multiple myeloma patients.
  Metho

  ..

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