Effect of added pharmatose dcl11 on metronidazole sustained release from methocel k4m and carbopol 971p nf floating matrices

• In: Industrial Pharmacy Section - Poster Session
• At: Salvadore (Brazil) (2006)
• Type: Poster
• Poster code: IPS-P-001
• By: VILLAFUERTE-ROBLES, Leopoldo (National Polytechnic Institute, Pharmacy, Mexico City, Mexico)
• Co-author(s): Cedillo-Ramírez, Erika (National Polytechnic Institute, MEXICO CITY, Mexico)
  Hernández-León, Alejandra (Universidad Autonoma Metropolitana, MEXICO CITY, Mexico)
  
• Abstract:

  In vitro dissolution of metronidazole sustained release from floating tablets has been studied varying the proportion of sodium bicarbonate (SB) and Pharmatose DCL 11. Two polymers with different hydration characteristics, Methocel K4M and Carbopol 971P NF, were used to formulate the matrices. The variables studied include the matrices release..

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