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A diclofenac sodium silk fibroin-chitosan microspheres : Preparation controlled-release in vitro and pharmacokinetic profile in rats

  • At: Amsterdam (the Netherlands) (2012)
  • Type: Poster
  • By: LIU, Chun (Suzhou Municipal Hospital, Department of Pharmacy, Suzhou, China)
  • Co-author(s): Yin, J.L. (Suzhou Municipal Hospital, Suzhou, China)
    Shang, E.N. (Suzhou Municipal Hospital, Suzhou, China)
    Zhang, X.N. (Soochow University, Suzhou, China)
  • Abstract:

    The preparation and pharmaceutical characteristics of diclofenac sodium loaded silk fibroin-chitosan microspheres (DS-SF/CS-MS)were studied.
    DS-SF/CS-MS was investigated using an emulsion crosslinking technique and glutaraldehyde as cross-linker. The encapsulation efficiency, loading efficiency, particle size and in vitro release characteristics


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Last update 4 October 2019

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