Therapeutic drug monitoring of meropenem is not enough without true MIC value

• In: Posters
• At: Amsterdam (the Netherlands) (2012)
• Type: Poster
• Poster code: HPS-P-060
• By: KIMURA, Elza (Universidade Estadual de Maringá, Pharmacy, Maringá, Brazil)
• Co-author(s): Magon, T.F.S (Universidade Estadual de Maringá, Maringá, Brazil)
  Pocas, C. (Universidade Estadual de Maringá, Maringá, Brazil)
  Menegucci, T.C (Universidade Estadual de Maringá, Maringá, Brazil)
  Leite, G.M.L. (Universidade Estadual de Maringá, Maringá, Brazil)
  Yamada, S.S. (Universidade Estadual de Maringá, Maringá, Brazil)
  Germano, A. (Universidade Estadual de Maringá, Maringá, Brazil)
  Tognin, M.C.B (Universidade Estadual de Maringá, Maringá, Brazil)
  
• Abstract:

  
  Background:
  Meropenem has been prescribed for nosocomial infection and its efficacy is determined by the duration in percentage (%) of the dosing interval above MIC (40%T>
  4xMIC), but in intensive care units (ICU), plasma monitoring of meropenem is not routinely performed.
  Aims:
  We quantified plasma concentration of meropenem from ICU patients and

  ..

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