Development of pectin/chitosan matrix tablets for colonic delivery of dexamethasone.

• In: Industrial Pharmacy Section - Poster Session
• At: Cairo (Egypt) (2005)
• Type: Poster
• Poster code: IPS-P-031
• By: MORTADA, Nahed (Pharmacy Faculty AinShams University, Pharmaceutics, Cairo, Egypt)
• Co-author(s): Abd ElHady (Pharmacy Faculty AinShams University, CAIRO, Egypt)
  Khairy (ADCO, CAIRO, Egypt)
  Coucha (Pharmacy Faculty AinShams University, CAIRO, Egypt)
  
• Abstract:

  Aim: Development of pectin:chitosan (P:C) based matrix tablets for colonic delivery of dexamethasone. Methods: Pectin and chitosan were mixed in different ratios viz 2:1, 6:1and 10:1 P:C. In vitro release studies were done in pHs 1.2, 5.5, 7.4 and 6.8. The tablets were investigated concerning the % matrix erosion, the % water uptake and the..

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