Development and validation of a drug release rate technique for hydrophilic and hydrophobic drug entities in liposomal dispersions and gels

• In: SIG Pharmaceutical Biotechnology - Poster Session
• At: Cairo (Egypt) (2005)
• Type: Poster
• Poster code: PB-P-009*
• By: NOUNOU, Mohamed Mahmoud (Pharmacy Faculty, Alexandria University, Department of Pharmaceutics, Alexandria, Egypt)
• Co-author(s): El-Khordagui (Pharmacy Faculty, Alexandria University, ALEXANDRIA, Egypt)
  Khalafallah (Pharmacy Faculty, Alexandria University, ALEXANDRIA, Egypt)
  Khalil (Pharmacy Faculty, Alexandria University, ALEXANDRIA, Egypt)
  
• Abstract:

  The development, evaluation and validation of a method for determining the rate of hydrophilic and hydrophobic drug entities release from different types of liposomal dispersions and gels using a dialysis method are described. Dibucaine base and 5-fluorouracil were used as model drugs for a hydrophobic and hydrophilic drug respectively. Aliquots..

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