Spectrophotometric determination of gemifloxacin mesylate (gfm) in tablets using surface response experimental design

• In: Industrial Pharmacy Posters
• At: Lisbon (Portugal) (2010)
• Type: Poster
• Poster code: IPS-P-021
• By: GARCIA, Cássia (Universidade Federal do Pampa - UNIPAMPA, Uruguaiana, Brazil)
• Co-author(s): Paim, Clésio (Universidade Federal do Rio Grande do Sul - UFRGS, PORTO ALEGRE, Brazil)
  Führ, Fernanda (Universidade Federal do Rio Grande do Sul - UFRGS, PORTO ALEGRE, Brazil)
  Miron, Diogo (Universidade Federal do Rio Grande do Sul - UFRGS, PORTO ALEGRE, Brazil)
  Steppe, Martin (Universidade Federal do Rio Grande do Sul - UFRGS, PORTO ALEGRE, Brazil)
  Schapoval, Elfrides (Universidade Federal do Rio Grande do Sul - UFRGS, PORTO ALEGRE, Brazil)
  
• Abstract:

  A simple, rapid and extractive spectrophotometric method was developed for the determination of gemifloxacin mesylate (GFM) in tablets. The method was based on the formation of orange ion-pair complex between the basic nitrogen of the drug and sulphonphthalein acid dye (bromocresol green) in pH 3.3 phthalate buffer. The formed complex was

  ..

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