Development of a ranitidine controlled release gastroretentive oral dosage form

• In: G20 - Short oral communications on Pharmaceutical Manufacturing and Drug Delivery Technologies on Wednesday, 3 September 2008, 9:00-11:49
• At: Basel (Switzerland) (2008)
• Type: Presentation
• By: COELHO, Pedro (Universidade Fernando Pessoa, Porto, Portugal)
• Co-author(s): Santos, Delfim (Faculdade de Farmácia U. Porto, Portugal)
  Bettini, Ruggero (Universitá Degli Studi di Parma, Italy)
  Colombo, Paolo (Universitá Degli Studi di Parma, Italy)
  Sonvico, Fabio (Universitá Degli Studi di Parma, Italy)
  Strusi, OrazioLuca (Universitá Degli Studi di Parma, Italy)
  
• Abstract:

  Ranitidine is a very soluble drug which half life is approximately 3 hours and that due to its physicochemical characteristics is better absorbed in the stomach and upper duodenum. Due to its characteristics it is a good candidate for a controlled release, gastrorentetive oral administration. Hydrophilic matrices are an easy yet effective way of

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