Tackling anti-microbial resistance, development of novel metallo-ß-lactamase inhibitors
- At: 2017 FIP Congress in Stockholm (Sweden)
- Type: Presentation
- By: BREM, Jurgen (Oxford University, Chemistry, Oxford, United Kingdom)
- Co-author(s): Jurgen Brem: Chemistry, Oxford University, Oxford, United Kingdom
The β-lactams remain the most important antibiotics in clinical use. The most important type of resistance to them is mediated via β-lactamases. The recent clinical introduction of avibactam as a serine-β-lactamase inhibitor is a major advance. However, the metallo-β-lactamases are of particular concern because they catalyse the hydrolysis of.. The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.