Simultaneous stereoselective analysis of venlafaxine and o-desmethylvenlafaxine enantiomers in human plasma by hplc-ms/esi using a vancomycin chiral column

• In: Miscellaneous - Posters
• At: Beijing (China) (2007)
• Type: Poster
• Poster code: M-P-019
• By: LIU, Wen (Xiangya Second Hospital, Changsha, China)
• Co-author(s): Wang, Feng (Xiangya Second Hospital, CHANGSHA, China)
  Li, Huande (Xiangya Second Hospital, CHANGSHA, China)
  
• Abstract:

  A high-performance liquid chromatography-electrospray ionization mass spectrometry (HPLC-MS/ESI) method for simultaneous stereoselective analysis of venlafaxine(VEN) and its major metabolite O-desmethylvenlafaxine(ODV) enantiomers in human plasma has been developed and validated. Chiral chromatography is performed on the CHRIOBIOTIC V..

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