Simultaneous stereoselective analysis of venlafaxine and o-desmethylvenlafaxine enantiomers in human plasma by hplc-ms/esi using a vancomycin chiral column
- At: 2007 FIP Congress in Beijing (China)
- Type: Poster
- By: LIU, Wen (Xiangya Second Hospital, Changsha, China)
- Co-author(s): Wang, Feng (Xiangya Second Hospital, CHANGSHA, China)
Li, Huande (Xiangya Second Hospital, CHANGSHA, China)
A high-performance liquid chromatography-electrospray ionization mass spectrometry (HPLC-MS/ESI) method for simultaneous stereoselective analysis of venlafaxine(VEN) and its major metabolite O-desmethylvenlafaxine(ODV) enantiomers in human plasma has been developed and validated. Chiral chromatography is performed on the CHRIOBIOTIC V.. The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.