The effects of cyp2c19 and cyp2c9 genotype on valproate clearance in patients with epilepsy in China
- At: 2007 FIP Congress in Beijing (China)
- Type: Poster
- By: BAI, Xiangrong (Xuan-wu Hospital, Beijing, China)
- Co-author(s): Jiang, dechun (Xuan-wu Hospital, Beijing, China)
Wang, yuqin (Xuan-wu Hospital, Beijing, China)
Qi, xiaolian (Xuan-wu Hospital, Beijing, China)
AIM To evaluate the effects of CYP2C19 and CYP2C9 polymorphisms on Valproate (VPA) clearance of epileptic patients in China in order to promote individualized medicine. METHODS To retrospective collect the demographic data and steady serum concentrations of VPA from 216 epileptic patients. The gene polymorphisms of CYP2Cl9 and CYP2C9 were examined.. The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.