Population pharmacokinetics of imatinib mesylate in nigerian patients with chronic myeloid leukemia

• In: SUBMITTED ORALS on Wednesday, 16 April 2014, 14:30-15:30
• At: PSWC, Melbourne (Australia) (2014)
• Type: Presentation
• By: ADEAGBO, Babatunde (Obafemi Awolowo University, Department of Pharmaceutical Chemistry, Ile-ife, Nigeria)
• Co-author(s): Bolaji, Oluseye (Obafemi Awolowo University, Ile-ife, Nigeria)
  Olugbade, Tiwalade (Obafemi Awolowo University, Ile-ife, Nigeria)
  Durosinmi, Muheez (Obafemi Awolowo University, Ile-ife, Nigeria)
  Bolarinwa, Rahaman (Obafemi Awolowo University, Ile-ife, Nigeria)
  Ogungbenro, Kayode (University of Manchester, Manchester, United Kingdom)
  
• Abstract:

  Background: Population pharmacokinetic studies of imatinib mesylate in Caucasian and Japanese patients with chronic myeloid leukaemia (CML) have shown inter-subject and inter-population clearance variabilities. However, no pharmacokinetic (PK) study has been conducted in an African population since the introduction of the drug.
  Aim: This study..

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