Simultaneous and comprehensive in vivo analysis of cytochrome p450 activity by using a cocktail approach in rats
- In: SUBMITTED ORALS on Wednesday, 16 April 2014, 14:00-15:30
- At: PSWC, Melbourne (Australia) (2014)
- Type: Presentation
- By: UCHIDA, Shinya (University of Shizuoka, School of Pharmaceutical Sciences, Department of Pharmacy Practice & Science, Shizuoka, Japan)
- Co-author(s): Tanaka, Shimako (University of Shizuoka, School of Pharmaceutical Sciences, Shizuoka, Japan)
Namiki, Noriyuki (University of Shizuoka, School of Pharmaceutical Sciences, Shizuoka, Japan)
Background: A cocktail approach can detect the activities of multiple cytochrome P450 (CYP) isoforms following the administration of multiple CYP-specific substrates in a single experiment. Few studies have reported the results of a comprehensive analysis of CYP activity in rats.
Aims: The aim of this study was to develop a simultaneous and.. The access to the whole abstract and if available the presentation file is available to FIP members and to congress participants of that specific congress.