Microdosing and pet studies in drug transporter research

• In: MINI SYMPOSIUM: MOLECULAR AND FUNCTIONAL IMAGING IN DRUG DEVELOPMENT AND EARLY CLINIC on Wednesday, 16 April 2014, 09:00-10:00
• At: PSWC, Melbourne (Australia) (2014)
• Type: Presentation
• By: SUGIYAMA, Yuichi (RIKEN Innovation Center, Tokyo, Japan)
• Abstract:

  Microdose clinical trials can be utilized for the purpose to gain pharmacokinetic information on a tentative drug candidate in human using labelled compound(s) and AMS or imaging technology using PET, or non-labelled compound(s) and LC/MS/MS, and to select drug candidate by ensuring adequate properties in early stage. Recently (2008-2012), the

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