Nanoparticles and skin: unmoveable objects and irresistible barrier
- At: 2014 FIP Congress in PSWC, Melbourne (Australia)
- Type: Presentation
- By: GUY, Richard (University of Bath, Pharmacy & Pharmacology, Bath, United Kingdom)
I. Background. Intact skin is a formidable barrier to the penetration of xenobiotics. Specifically, the stratum corneum limits very efficiently the inward transport of chemicals contacting the skin, and structure-transport relationships show that lipophilicity and size are the crucial determinants of (trans)dermal absorption.
II. Aims... The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.