Synthesis & pharmacological evaluation of 1, 4-dihydro-4-oxo-1, 8-naphthyridine-3-carboxylic acid derivatives as antihistaminic agents.

• In: Medicinal Chemistry Posters
• At: Hyderabad (India) (2011)
• Type: Poster
• Poster code: MC-P-01
• By: GAJBHIYE, Asmita (Department of Pharmaceutical Sciences, Dr H.S.Gour Central University, Sagar, India)
• Co-author(s): Gurjar, Vinod (Department of Pharmaceutical sciences, Dr H.S.Gour Central university, Sagar, India)
  Patil, Shailendra (Department of Pharmaceutical sciences,Dr H.S.Gour Central university, Sagar, India)
  
• Abstract:

  1,8 Naphthyridine derivatives are important chemotherapeutic agents & possess various pharmacological activities like anti-inflammatory, analgesic, 5-HT3 antagonist, antiplatelet, PDE-5 inhibitory, A1 adenosine antagonists, A2A adenosine receptors agonist & antiallergic activity.
  Azelastine, an asthma prophylactic, contains 3 pharmacophoric

  ..

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