Molecular Trojan horses for blood brain barrier drug delivery

• In: S4 - Targeted drug delivery: From Concept to Clinical reality on Tuesday, 2 September 2008, 14:00-17:00
• At: Basel (Switzerland) (2008)
• Type: Presentation
• By: BOADO, Ruben (UCLA, Los Angeles, United States of America)
• Abstract:

  The progress in the development of biotherapeutics for the treatment of disorders of the central nervous system is impaired by the presence of the blood-brain barrier (BBB), which is only permeable to lipophilic molecules of <400 Da. Neuronal growth factors, i.e. BDNF and GDNF, are potential neuroprotective agents for the treatment of stroke,

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