Effect of cyp2d6, cyp3a5 and mdr1 genetic polymorphisms on the pharmacokinetics of risperidone and its active moiety
- In: Individualised Medicine - Posters
- At: Istanbul (Turkey) (2009)
- Type: Poster
- Poster code: IM-P-006
- By: CUI, Yimin (Department of Pharmacy, Peking University First Hospital, Beijing, China)
- Co-author(s): Xiang, Qian (Department of Pharmacy, Peking University First Hospital, BEIJING, China)
Zhao, Xia (Department of Pharmacy, Peking University First Hospital, BEIJING, China)
Zhou, Ying (Department of Pharmacy, Peking University First Hospital, BEIJING, China)
Duan, Jingli (Peking University Third Hospital, BEIJING, China) - Abstract:
AIMS
Clinical studies suggest that plasma levels of risperidone and its active moiety (risperidone + 9-hydroxyrisperidone) correlate with adverse drug effects. The aim of this study was to evaluate the pharmacogenetic variability in the disposition of risperidone and the active moiety in healthy Chinese subjects.
METHODS
A two milligram.. The access to the whole abstract and if available the presentation file is available to FIP members and to congress participants of that specific congress.
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Last update 28 September 2023