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Plasma-mediated covalent bonding of rhamnolipids onto PDMS surface as a strategy to overcome vascular catheter-related infections

  • At: Seville (Spain) (2022)
  • Type: Poster
  • Poster code: DDD-025
  • By: RIBEIRO, Isabel ()
  • Co-author(s): PhD Dardouri Maissa (Research Institute for Medicines, iMed.Ulisboa, Faculty of Pharmacy, Universidade de Lisboa, Lisboa, Portugal)
    PhD Ana Bettencourt (Research Institute for Medicines, iMed.Ulisboa, Faculty of Pharmacy, Universidade de Lisboa, Lisboa, Portugal)
    MSc. Victor Martin (BoneLab - Laboratory for Bone Metabolism and Regeneration – Faculty of Dental Medicine, U. Porto Rua Dr. Manuel Pereira da Silva, 4200-393 Porto, Portugal / LAQV/REQUIMTE, U. Porto, Porto, 4160-007, Portugal.)
    PhD Filomena A. Carvalho (Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Av. Prof. Egas Moniz, 1649-028 Lisbon, Portugal)
    PhD Catarina Santos (CQE Instituto Superior Técnico, Universidade de Lisboa, Av. Rovisco Pais 1049-001, Lisboa, Portugal. / EST Setúbal, CDP2T, Instituto Politécnico de Setúbal, Campus IPS, 2910 Setúbal, Portugal.)
    PhD Nuno C. Santos (Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Av. Prof. Egas Moniz, 1649-028 Lisbon, Portugal)
    PhD Maria Fernandes (BoneLab - Laboratory for Bone Metabolism and Regeneration – Faculty of Dental Medicine, U. Porto Rua Dr. Manuel Pereira da Silva, 4200-393 Porto, Portugal / LAQV/REQUIMTE, U. Porto, Porto, 4160-007, Portugal.)
    PhD Pedro Gomes (BoneLab - Laboratory for Bone Metabolism and Regeneration – Faculty of Dental Medicine, U. Porto Rua Dr. Manuel Pereira da Silva, 4200-393 Porto, Portugal / LAQV/REQUIMTE, U. Porto, Porto, 4160-007, Portugal.)
    Prof Isabel Ribeiro (Research Institute for Medicines, iMed.Ulisboa, Faculty of Pharmacy, Universidade de Lisboa, Lisboa, Portugal)
  • Abstract:

    Introduction: Fighting bacterial biofilm formation on Poly(dimethylsiloxane) (PDMS)-based bloodstream catheters is of major concern in order to reduce the occurrence of related infections.
    Aim: In this study, rhamnolipids (RLs), glycolipid biosurfactants, namely a RLs mixture and purified di-RL (RhaRhaC10:0C10:0), were covalently bound onto PDMS..

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Last update 28 September 2023

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